Joint Health

In multiple research papers, ACTIV+LIFE® products support joint health when consumed daily with patented formula Fortigel®

FORTIGEL® promotes the growth of cartilage tissue

The effectiveness of FORTIGEL® has been scientifically demonstrated in numerous studies that have shown that, when administered orally, it is absorbed by the intestines and then accumulates in the cartilage. The intake of FORTIGEL® stimulates, statistically, a significant increase in cartilage metabolism.

Alindon idr. (2011)

Clark idr. (2008)

Flechsenhar (2007)

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Tendons & Ligaments Health

Scientific studies have shown that specific Bioactive Collagen Peptides stimulate the biosynthesis of collagen, proteoglycans and elastin in Achilles tendon and ligament fibroblasts.

Bioactive Collagen Peptides like TENDOFORTE® has been proven as a nutrition solution to support strong and flexible tendons & ligaments contributing to the foundation of high performance and fast return-to-training in athletes. 

Recent study shows the efficacy of TENDOFORTE®

A study of the Australian Institute of Sport (AIS) examined the benefits of TENDOFORTE® supplementation over a period of 6 months (cross-over design). The participants were 20 subjects with long-term symptoms of chronic Achilles tendinopathy, not responding to any traditional therapies and being unable to train. Within 3 months, 12 out of 20 participants were able to return to running after starting a therapy with daily intake of 5 g TENDOFORTE® in combination with a highly specialized exercise program. Furthermore, the effect is long-term. The group starting with TENDOFORTE® in the cross-over design still had beneficial effects after the 3 months wash-out phase.

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Skin Health

VERISOL®, scientifically proven Bioactive Collagen Peptides®, stimulates skin metabolism and collagen production in the deep layers of the skin. Biotin und Niacin contribute to the preservation of normal skin.

Orally applied, VERISOL® systematically effects the collagen metabolism in the dermis rather than just reaching the outer layers of the skin like creams and other topical products do.

Higher skin elasticity1

The first study with 69 women aged between 35 and 55 years revealed that VERISOL® leads to significantly higher skin elasticity – up to 15 % – compared to placebo treatment. This effect could be measured after just 4 weeks of treatment and persisted after 8 weeks of oral VERISOL®administration. Another 4 weeks after the last intake of the product, VERISOL® application still showed higher skin elasticity levels than in the placebo treated group.

Skin elasticity increased significantly afteroral VERISOL® treatment in comparison to placebo administration.

Oral Supplementation of Specific Collagen Peptides Has Beneficial Effects on Human Skin Physiology: A Double-Blind, Placebo-Controlled Study
Proksch E., Segger D., Degwert J., Schunck M., Zague V., Oesser S. Skin Pharmacol Physiology, August 2013

Reduction of wrinkles2

The second study with more than 100 women aged between 45 and 65 years shows that the oral administration of VERISOL® (2.5 g/day) significantly reduces wrinkles after 4 weeks and leads to a significantly higher skin procollagen concentration.

VERISOL® significantly reduces wrinkles: The collagen in the skin increases by 60%.

Oral Intake of Specific Bioactive Collagen Peptides Reduces Skin Wrinkles and Increases Dermal Matrix Synthesis
Proksch E., Schunck M., Zague V., Segger D., Degwert J., Oesser S. Skin Pharmacol Physiology, December 2013

Improved skin surface structure and decrease of cellulite

About 85 % of the global female adult population is affected by cellulite (the orange peel appearance of skin). Cellulite is a beauty aspect, not a disease, but many women suffer from this beauty flaw. Cellulite is mainly caused by dermal matrix disturbances, in combination with excess of subcutaneous fat, bulging into the dermis as well as excess of intersistal fluid.

VERISOL® supplementation has beneficial effects on the dermal extracellular matrix of the skin and can help to decrease cellulite. Contrary to current cellulite supplements that mainly address the aspects of excessive fat or microcirculation/drainage, VERISOL® directly stimulates the extracellular matrix formation in skin.

Density of dermis (ultrasound measurement)

Significant decrease of waviness

Significant higher dermal density after 6 month

Significant decrease of cellulite score3

A double blind, randomized, placebo controlled study with 105 women aged between 25 and 50 years shows that the daily oral intake of 2.5 g VERISOL® significantly decreases the cellulite score. The effect was measured after 3 and 6 months supplementation. VERISOL® has a beneficial effect on skin extracellular matrix and restores the normal structure of the dermis and subcutaneous tissue. VERISOL® supplementation also reduced the waviness of the skin, with first results visible after 3 months, but more pronounced after 6 months. With a daily dose of 2.5 g VERISOL® the appearance of cellulite women with a BMI < 25 was significantly reduced.

As part of the study, changes in the dermal density were investigated. The two ultrasound scans show side by side the skin of a participant in the placebo group compared to the skin of a participant from the VERISOL® group. The increase in elastin and collagen is clearly visible.

3 JOURNAL OF MEDICINAL FOOD, J Med Food 00 (0) 2015, 1–9, DOI: 10.1089/jmf.2015.0022, Dietary Supplementation with Specific Collagen Peptides Has a Body Mass Index-Dependent Beneficial Effect on Cellulite Morphology
Michael Schunck, 1 Vivian Zague, 2 Steffen Oesser, 1 Ehrhardt Proksch, 3

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